Martha “Mattie” Kennedy (nee Luney) Holmes was born in Ireland in 1874 and came with her family to the United States as a young girl. In 1894, she married Dr. William Wesley Holmes, who was 30 years her senior. After William’s death in 1913, Mattie worked as a traveling and home nurse.
I’m not sure when Mattie died. She was living with her sister, Edith Cole, in Yonkers, New York in 1930. The last trace I found of her was in 1936 when she was still in Yonkers, but living on her own at 472 Hawthorne.
The Denison Review, Denison, Iowa, February 12, 1913, – William Holmes’ obituary
Yonkers, New York City Directory 1931 and 1936